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Thymalin

Thymalin (Thymulin) is a nonapeptide hormone originally isolated from the thymus gland. Research investigations are examining its immunomodulatory properties and interactions with T-lymphocyte differentiation pathways. Studies explore its biochemical effects on immune cell maturation, cytokine production, and neuroendocrine-immune interactions. Scientists continue to investigate its role in thymic function and immune system regulation research. This material is for research purposes only and is not intended for human use.

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Description

Thymulin, also known as Thymalin or thymic factor, is a nonapeptide hormone produced by the epithelial cells of the thymus gland. It plays a crucial role in the maturation and differentiation of T-lymphocytes, which are essential for a healthy immune response. The biological activity of Thymulin is dependent on the presence of zinc, forming a metallopeptide complex. Its primary mechanism of action involves modulating the immune system by promoting the development of T-cells and enhancing their function, including the activity of Natural Killer (NK) cells. Research has highlighted Thymulin’s immunomodulatory and anti-inflammatory properties, making it a subject of investigation for a variety of conditions. Key research areas include its potential therapeutic use in autoimmune diseases, age-related immune decline (immunosenescence), and neuroinflammatory disorders. Studies have also explored its role in the intricate communication between the neuroendocrine and immune systems. This product is intended for research purposes only and is not for human or veterinary use.

CAS: 63958-90-7
PubChem CID: 3085284
Molecular Formula: C₃₃H₅₄N₁₂O₁₅
Molecular Weight: 858.86 g/mol
Amino Acid Sequence: Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn (9 aa)
Physical Form: Lyophilized Powder
Purity: ≥99%
Storage: -20°C, protected from light and moisture