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NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme found in all living cells. Research investigations are examining its role in cellular redox reactions, energy metabolism, and sirtuin enzyme activation. Studies explore its involvement in DNA repair pathways, mitochondrial function, and cellular senescence mechanisms. Scientists continue to investigate its biochemical significance in metabolic regulation and aging-related research. This material is for research purposes only and is not intended for human use.

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Description

Nicotinamide Adenine Dinucleotide (NAD+) is a fundamental coenzyme that is present in every living cell and plays a critical role in a wide array of biological processes. As a key component of cellular metabolism, NAD+ is essential for the redox reactions that drive energy production. It functions as an oxidizing agent, accepting electrons from various metabolic reactions and being reduced to NADH, which then donates these electrons to the electron transport chain for ATP synthesis.

Beyond its role in energy metabolism, NAD+ serves as a crucial substrate for several enzyme families, including sirtuins and poly(ADP-ribose) polymerases (PARPs). Sirtuins, which are implicated in aging and longevity, utilize NAD+ to deacetylate proteins, thereby regulating gene expression and cellular stress responses. PARPs, on the other hand, are involved in DNA repair and the maintenance of genomic stability, consuming NAD+ in the process.

Given its multifaceted roles, research into NAD+ has expanded into numerous areas, including age-related diseases, neurodegenerative disorders such as Alzheimer’s, cardiovascular health, and metabolic conditions. Studies are actively exploring the therapeutic potential of modulating NAD+ levels to address these conditions.

This product is intended for research purposes only and is not for human consumption.

CAS: 53-84-9
PubChem CID: 5892
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: 663.43 g/mol
Amino Acid Sequence: N/A (dinucleotide coenzyme)
Physical Form: Lyophilized Powder
Purity: ≥99%
Storage: -20°C, protected from light and moisture