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  • Product Usage Notice: This product is intended strictly for research and laboratory use only. It is designated for in vitro testing and experimental purposes. Any use involving human or animal consumption is prohibited by law. All information provided on this website is for educational purposes only. This product must only be handled by licensed, qualified professionals. It is not intended for use as a drug, food, or cosmetic, and must not be misused, mislabeled, or misrepresented as such.
MOTS-C

MOTS-C

MOTS-C is a mitochondria-derived peptide encoded within the mitochondrial genome. Research investigations are examining its role in mitochondrial function, metabolic homeostasis, and cellular bioenergetics. Studies explore its interactions with AMPK signaling pathways and its effects on glucose metabolism in laboratory models. Scientists continue to investigate its involvement in exercise physiology research and aging-related metabolic pathways. This material is for research purposes only and is not intended for human use.

Price range: $90.00 through $265.00

  • Peptides will arrive in a lyophilized (powder) form for maximum stability
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Description

MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a novel 16-amino acid peptide encoded by the mitochondrial genome that plays a crucial role in metabolic regulation and cellular homeostasis. Its primary mechanism of action involves the activation of the AMP-activated protein kinase (AMPK) pathway, a master regulator of cellular energy metabolism. By activating AMPK, MOTS-c enhances glucose uptake and utilization in skeletal muscle, improves insulin sensitivity, and promotes fatty acid oxidation.

Key research areas for MOTS-c include its potential therapeutic applications in metabolic disorders such as type 2 diabetes, obesity, and non-alcoholic fatty liver disease. Studies have also demonstrated its role in regulating bone metabolism, preventing muscle atrophy, and modulating inflammatory responses. As a mitochondrial-derived peptide, MOTS-c is at the forefront of research into mitochondria-to-nucleus signaling and its impact on aging and age-related diseases.

This product is intended for research purposes only and is not for human consumption.

CAS: 1627580-64-6
PubChem CID: 146675088
Molecular Formula: C101H152N28O22S2
Molecular Weight: 2174.62 g/mol
Amino Acid Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (16 aa)
Physical Form: Lyophilized Powder
Purity: ≥99%
Storage: -20°C, protected from light and moisture