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Note: Current 50mg batch was underfilled from manufacturer. Pricing is discounted to reflect this.
SS-31 is a synthetic mitochondria-targeting tetrapeptide with aromatic-cationic properties. Research investigations are examining its interactions with cardiolipin and inner mitochondrial membrane structures. Studies explore its biochemical effects on mitochondrial electron transport, oxidative phosphorylation, and reactive oxygen species generation. Scientists continue to investigate its mitochondrial protective properties and bioenergetic mechanisms. This material is for research purposes only and is not intended for human use.
Price range: $65.00 through $195.00
Elamipretide (SS-31) is a novel, cell-penetrating tetrapeptide that represents a significant advancement in the field of mitochondrial medicine. Its unique mechanism of action involves selectively targeting and binding to cardiolipin, a crucial phospholipid component of the inner mitochondrial membrane. This interaction plays a vital role in preserving mitochondrial structure and function, particularly under conditions of cellular stress. By stabilizing the mitochondrial cristae, Elamipretide enhances the efficiency of the electron transport chain, leading to optimized ATP synthesis and a reduction in the production of harmful reactive oxygen species (ROS). This restoration of mitochondrial bioenergetics makes Elamipretide a promising therapeutic candidate for a range of conditions associated with mitochondrial dysfunction.
Key areas of research for Elamipretide include its potential applications in treating Barth syndrome, a rare genetic disorder characterized by mitochondrial abnormalities, as well as more common age-related diseases such as heart failure, macular degeneration, and neurodegenerative disorders. Studies have also explored its efficacy in improving outcomes in conditions like Leber’s Hereditary Optic Neuropathy and myopathic mitochondrial DNA depletion syndrome. Further investigations are ongoing to fully elucidate its therapeutic potential across a spectrum of diseases.
This product is intended for research purposes only and is not for human or veterinary use.
CAS: 736992-21-5
PubChem CID: 11764719
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: 639.79 g/mol
Amino Acid Sequence: D-Arg-Dmt-Lys-Phe-NH₂ (4 aa, modified)
Physical Form: Lyophilized Powder
Purity: ≥99%
Storage: -20°C, protected from light and moisture
