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DSIP

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide originally isolated from rabbit brain tissue. Research investigations are exploring its interactions with various neurological pathways and its role in circadian rhythm biochemistry. Studies are examining its effects on neuroendocrine signaling, stress response mechanisms, and sleep architecture in laboratory models. This material is for research purposes only and is not intended for human use.

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Description

Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide composed of nine amino acids. First isolated in 1977, DSIP is primarily known for its role in the regulation of sleep, particularly its ability to promote slow-wave sleep (delta sleep). Its mechanism of action involves complex interactions within the central nervous system, where it modulates the sleep-wake cycle and influences the circadian rhythm through interactions with key neurotransmitters like serotonin and melatonin. Beyond its effects on sleep, research has indicated that DSIP possesses a broader range of physiological activities. Studies have explored its potential as a potent antioxidant, its ability to modulate stress hormone levels, and its influence on the release of other hormones such as luteinizing hormone (LH) and growth hormone-releasing hormone (GHRH). Key areas of ongoing research include its potential applications in managing sleep disorders, its role in stress adaptation, and its neuroprotective effects in the context of age-related cognitive decline. This product is intended for research purposes only and is not for human or veterinary use.

CAS: 62568-57-4
PubChem CID: 68816
Molecular Formula: C₃₅H₄₈N₁₀O₁₅
Molecular Weight: 848.81 g/mol
Amino Acid Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (9 aa)
Physical Form: Lyophilized Powder
Purity: ≥99%
Storage: -20°C, protected from light and moisture